A series of road closures around the state are set to keep motorists out of the country, as the powerful storm headed towards the central plains.
While it is not expected to affect travel in the area, it will cause problems with emergency vehicles and other emergency services, as well as be difficult to access for some people.
It is not unusual for people to experience travel problems after heavy rains, particularly in the central, western and southern Plains, said Bill Fitch, a spokesman for the Colorado Department of Transportation.
The most significant road closures will begin in Fort Collins, Colorado, at 10 p.m. local time on Monday, and move south, ending at the town of Grand Junction, at 6 a.m., said spokeswoman Mary-Ann Martin.
In the western part of the state, the heaviest rain will hit from the northern part of Fort Collins to the western parts of Laramie and Fort Wayne, according to the Colorado Bureau of Transportation and the National Weather Service.
It will remain heavy until Wednesday afternoon, when the rain will begin to fade and the storms will ease.